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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
21/02/2014 |
Actualizado : |
18/12/2018 |
Tipo de producción científica : |
Artículos Indexados |
Autor : |
AGUILAR, I.; LEGARRA, A.; TSURUTA, S.; MISZTAL, I. |
Afiliación : |
IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Genetic evaluation using unsymmetric single step genomic methodology with large number of genotypes. |
Fecha de publicación : |
2013 |
Fuente / Imprenta : |
Interbull Bulletin, 2013, v. 47, p. 222-225. |
Idioma : |
Inglés |
Contenido : |
ABSTRACT.
The single step genomic methodology provides a unified framework to integrate phenotypic, pedigree and genomic information in the prediction of breeding values. Minimal modifications of current softwares are necessary in order to incorporate extra relationship matrices, however computing such matrices has a cubic cost. Recently, a system of equations relaxing the computing cost of creating the inverse of the genomic relationship matrix was presented, which creates an unsymmetric system of equations. Bi Conjugate Gradient Stabilized solvers (BiCGSTAB) were proposed to solve unsymmetric system of equations and also can be used with iteration on data programs, resulting in a good choice for solving large-scale genetic evaluations. Here we describe the implementation of a large genetic evaluation using unsymmetric solvers within the iteration on data framework. Comparison with the regular single-step methodology is presented and the effects of different preconditioners and data structures on the convergence pattern were studied. A large scale genetic evaluation was feasible, however required more rounds to get convergence compared with the regular single-step. More sophisticated preconditioners are necessary to improve the convergence for solving unsymmetric single-step genomic evaluations. |
Palabras claves : |
BICGSTAB; GENETIC EVALUATION; GENOMIC SELECTION; SINGLE-STEP. |
Asunto categoría : |
-- |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/12205/1/1326-2215-1-PB.pdf
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Marc : |
LEADER 01912naa a2200205 a 4500 001 1012459 005 2018-12-18 008 2013 bl uuuu u00u1 u #d 100 1 $aAGUILAR, I. 245 $aGenetic evaluation using unsymmetric single step genomic methodology with large number of genotypes.$h[electronic resource] 260 $c2013 520 $aABSTRACT. The single step genomic methodology provides a unified framework to integrate phenotypic, pedigree and genomic information in the prediction of breeding values. Minimal modifications of current softwares are necessary in order to incorporate extra relationship matrices, however computing such matrices has a cubic cost. Recently, a system of equations relaxing the computing cost of creating the inverse of the genomic relationship matrix was presented, which creates an unsymmetric system of equations. Bi Conjugate Gradient Stabilized solvers (BiCGSTAB) were proposed to solve unsymmetric system of equations and also can be used with iteration on data programs, resulting in a good choice for solving large-scale genetic evaluations. Here we describe the implementation of a large genetic evaluation using unsymmetric solvers within the iteration on data framework. Comparison with the regular single-step methodology is presented and the effects of different preconditioners and data structures on the convergence pattern were studied. A large scale genetic evaluation was feasible, however required more rounds to get convergence compared with the regular single-step. More sophisticated preconditioners are necessary to improve the convergence for solving unsymmetric single-step genomic evaluations. 653 $aBICGSTAB 653 $aGENETIC EVALUATION 653 $aGENOMIC SELECTION 653 $aSINGLE-STEP 700 1 $aLEGARRA, A. 700 1 $aTSURUTA, S. 700 1 $aMISZTAL, I. 773 $tInterbull Bulletin, 2013$gv. 47, p. 222-225.
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INIA Las Brujas (LB) |
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Registros recuperados : 45 | |
4. | | MASUDA, Y.; AGUILAR, I.; TSURUTA, S.; MISZTAL, I. Acceleration of computations in AI REML for single-step GBLUP models. Volume Methods and Tools: Statistical methods - linear and nonlinear models (Posters), 703. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.703.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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6. | | TSURUTA, S.; MISZTAL, I.; AGUILAR, I.; LAWLOR, T. J. Genome wide association study on cow mortality in three US regions. Volume Species Breeding: Dairy cattle (Posters), 805. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.805.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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8. | | AGUILAR, I.; MISZTAL, I.; LEGARRA, A.; TSURUTA, S. Efficient computations of genomic relationship matrix and other matrices used in the single-step evaluation. Volume Methods and tools: Software and bioinformatics - Lecture Sessions, 0768. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0768. Acknowledgments: This study was partially funded by the Holstein Association USA Inc. and by AFRI grants 2009-65205-05665 and 2010-65205-20366 from the USDA NIFA Animal Genome Program. The authors thank P.M. VanRaden from Animal...Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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9. | | TSURUTA, S.; MISZTAL, I.; AGUILAR, I.; LAWLOR, T.J. Multiple-trait genomic evaluation of linear type traits using genomic and phenotypic data in US Holsteins. Journal of Dairy Science, 2011, v.94, no.8, p.4198-4204. OPEN ACCESS. Article history: Received February 9, 2011. / Accepted April 8, 2011.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 1 |
Biblioteca(s): INIA Las Brujas. |
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10. | | AGUILAR, I.; MISZTAL, I.; TSURUTA, S.; LEGARRA, A.; WANG, H. PREGSF90 - POSTGSF90: Computational tools for the implementation of single-step genomic selection and genome-wide association with ungenotyped individuals in BLUPF90 programs. Volume Methods and Tools: Statistical and genomic tools for mapping QTL and genes (Posters), 680. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.680.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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11. | | MASUDA, Y.; AGUILAR, I.; TSURUTA, S.; MISZTAL, I. Technical note: Acceleration of sparse operations for average-information REML analyses with supernodal methods and sparse-storage refinements. Journal of Animal Science, 2015, v. 93, p. 4670 - 4674. Published October 9, 2015 Article history: Received June 8, 2015.; Accepted August 7, 2015.
1. We acknowledge the work by François Guillaume in programming a hash function. We greatly appreciate the work of the two anonymous reviewers.
2. The AIREMLF90 program...Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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12. | | GARCÍA, A.; AGUILAR, I.; LEGARRA, A.; MILLER, S.; TSURUTA, S.; MISZTAL, I.; LOURENCO, D. Accuracy of indirect predictions for large datasets based on prediction error covariance of SNP effects from single-step GBLUP. [abstract 22]. Issue Section: Animal Breeding and Genetics. Journal of Animal Science, 2020, Volume 98, Issue Supplement 4, Pages 6-7. doi: https://doi.org/10.1093/jas/skaa278.012 Article history: 30 November 2020.
ASAS Annual 2020 Meeting Abstracts.Tipo: Abstracts/Resúmenes |
Biblioteca(s): INIA Las Brujas. |
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13. | | LOURENÇO, D. A. L.; MISZTAL, I.; TSURUTA, S.; FRAGOMENI, B.; AGUILAR, I.; MASUDA, Y.; MOSER, D. Direct and indirect genomic evaluations in beef cattle. Interbull Bulletin, 2015, v. 49, p.80 - 84.Tipo: Artículos Indexados |
Biblioteca(s): INIA Las Brujas. |
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15. | | LOURENCO, D; MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LAWLOR, T. J.; WELLER, J. I. Are evaluations on young genotyped dairy bulls benefiting from the past generations? [conference paper]. Volume Species Breeding: Dairy cattle, 297. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.297.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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16. | | AGUILAR, I.; TSURUTA, S.; MASUDA, Y.; LOURENCO, D.A.L.; LEGARRA, A.; MISZTAL, I. BLUPF90 suite of programs for animal breeding with focus on genomics. Volume Methods and Tools - Software, p. 751. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018. 6 p.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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17. | | GARCÍA, A.; AGUILAR, I.; LEGARRA, A.; TSURUTA, S.; MISZTAL, I.; LOURENCO, D. Correction: Theoretical accuracy for indirect predictions based on SNP effects from single-step GBLUP (Genetics, selection, evolution : GSE (2022) 54:1 (66)). Genetics, Selection, Evolution : GSE, 2023, Volume 55, Issue 1, Pages 26. OPEN ACCESS. https://doi.org/10.1186/s12711-023-00799-x Article history: Published online 17 April 2023. -- Document: Erratum - Gold Open Access. -- The original article can be found online at https://doi.org/10.1186/s12711-022-00752-4Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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18. | | MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LEGARRA, A.; VAN RADEN, P.M.; LAWLOR, T.J. Methods to approximate reliabilities in single-step genomic evaluation. Journal of Dairy Science, 2013, v.96, no.1, p.647-654. OPEN ACCESS. Article history: Received April 24, 2012. / Accepted September 18, 2012.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 1 |
Biblioteca(s): INIA Las Brujas. |
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19. | | AGUILAR, I.; MISZTAL, I.; JOHNSON, D.L.; LEGARRA, A.; TSURUTA, S.; LAWLOR, T.J. Hot topic: A unified approach to utilize phenotypic, full pedigree, and genomic information for genetic evaluation of Holstein final score. Journal of Dairy Science, 2010, v. 93, no. 2, p. 743-752. OPEN ACCESS Article history: Received September 14, 2009 / Accepted November 10, 2009 / Published in issue: February 2010.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 1 |
Biblioteca(s): INIA Las Brujas. |
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20. | | MISZTAL, I.; LOURENCO, D.; TSURUTA, S.; AGUILAR, I.; MASUDA, Y.; BERMANN, M.; CESARANI, A.; LEGARRA, A. How ssGBLUP became suitable for national dairy cattle evaluations. [668]. Part 37 - Bovine dairy - genetic evaluation methods. In: Proceedings of the World Congress on Genetics Applied to Livestock Production (WCGALP), 12., Rotterdam, the Netherlands, 3-8 July 2022. doi: https://doi.org/10.3920/978-90-8686-940-4_668 2757-2760. Article history: Published online: February 9, 2023 -- Corresponding author: I. Misztal, email: ignacy@uga.eduTipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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Registros recuperados : 45 | |
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